As known from:
VA
  • Our US Squad
  • Our Mission
  • How We Rate Betting Sites
PlayersBest.com / PlayersBest News / March Madness Betting Guide

March Madness Betting Guide: Early Sweet 16 & Championship Winners

Publish Date: 03/16/2022
Fact checked by: David Howard

March Madness play in games are underway, but the main tournament starts Thursday the 17th. Selection Sunday was kind to certain teams (Rutgers, Notre Dame, Wyoming, & Michigan), while shunning other teams to the NIT (Oklahoma, Texas A&M, Wake Forest, & Xavier). Picking brackets is a timeless tradition. However, placing bets on which underdogs will make it to the Sweet 16 can maximize your winnings. Furthermore, placing bets now for National Championship winners can ensure the best odds. Find the best places to place your bets with the Top Basketball Betting Sites tool.

March Madness Odds

Biggest Upsets for the Sweet 16

Virginia Tech Hokies +250

The number 11 seed Virginia Tech Hokies have better odds to make it to the Sweet 16 than the number six seed Texas Longhorns. Virginia Tech is on a four game winning streak as they beat Duke for the ACC Tournament Championship. Virginia Tech will probably face Purdue in the Round of 32. Though, Purdue has been struggling lately themselves.

Murray State Racers +600

The Racers are a number seven seed, and will have to face the USF Dons. San Francisco is a tricky team and just getting by them will be tough, but very possible for the 30 win Racers, who basically only lost to Auburn this year. Murray State over Kentucky may be too controversial, but they match up well against Kentucky and could pull off the Cinderella Story, at least until the Sweet 16.

Colorado State Rams +800

Despite being only a six seed, the Rams have one of the worst odds to make the Sweet 16. This is because they are going up against the most overrated Michigan squad who have an embarrassing high odd of +225 for the Sweet 16. Avoid the Wolverines at all cost, they are not a good team this year, and lead by Juwan Howard has been embarrassing. The Rams will take on Tennessee, and surprisingly match up well against the Vols. David Roddy is a beast on the court, go Rams!

Best March Madness Services

Odds On Who Will Be The National Champion

Gonzaga Bulldogs +300

The Zags top most brackets with Chet Holmgren and Drew Timme leading the charge. The number one seeded Zags will have to win the West, potentially facing teams like Boise State, UCONN, Texas Tech and/or Duke. They will also have to win against the winner of the East, which holds both Baylor, Kentucky, & Purdue.

Arizona Wildcats +600

The path for the number one seeded Wildcats will be tough in the South. either Houston or Illinois will pose a challenge as well as either Colorado State, Tennessee, or Villanova. They will also have to face off against the winner of the Midwest (Kansas, Iowa, Auburn) just to make the National Championship game.

Kansas Jayhawks +900

The Jayhawks will have to win out the Midwest and then play the South to make the final game of the Big Dance. Kansas has a tough task of either San Diego State or Creighton, then probably Iowa, Auburn, and then Arizona to win it all. Iowa has a much better payout for a hotter team in the Midwest.

Baylor Bears +1200

Waco, Texas is nowhere near the East, but do the names of the regions really mean anything? Baylor is looking to win back to back championships, but don’t look as good as last year. They will have to win the East with Kentucky, Purdue, and some of the biggest possible teams to make a Cinderella run in Murray State, San Francisco, Saint Mary’s, and Virginia Tech. Of course UCLA plays well in March too.

Tennessee Volunteers +1800

As established earlier, the Volunteers will have to play in the South. This looks like the hardest region in the tournament with Colorado State, Ohio State, Villanova, Loyola Chicago, Illinois, & Houston. If it is not Arizona on this side of the bracket, I’d look at Tennessee next if they can survive Colorado State.

Iowa Hawkeyes +2500

Iowa will get red-hot Richmond in the first round, though Iowa is hot themselves. Furthermore, the Hawkeyes won the Big Ten Tournament and won 12 of their last 14 matchups (One of those two losses were to Illinois, 74-72). Iowa will likely have to beat Kansas, Auburn, and Arizona before playing in the National Championship game. I like their odds best overall for the Midwest.

Whether betting for March Madness or Major League Baseball, utilize the Sportsbook Odds Comparisons to find the best odds.

Read Also
College Basketball’s Big 10 Conference Tournament Betting Guide
The Big 10 Conference Tournament will likely be as wild as the ...
Rutgers vs Indiana: College Basketball Betting Guide
March Madness kicks off March 15th, with Selection Sunday on the 13th. ...
BetMGM Promo
March Madness 2022 Betting Guide
The NCAA basketball tournament is right around the corner, and today we ...
Michigan vs Iowa: College Basketball Betting Guide
The 13-10 Michigan Wolverines go to Iowa City to take on the ...
Late January College Basketball Preview & Upset Watch
There were lots of good games this past week, including #1 Auburn ...
Latest News
How Do Sweepstakes Casinos Work? – A Brief Intro to Sweeps Casinos
Sweepstakes casinos and social casinos are big news ...
Social Casino Stocks – The Best Options Available
The casino sector has long been a favorite ...
Virginia Limits Sportsbook Tax Deductions For Promotional Offers
Virginia online sportsbooks have enjoyed the ability to ...
Cincinnati Bengals Ink Their First Sports Betting Partnership
The imminent launch of legalized sports betting in ...
California Democratic Party Confirms Opposition to Online Sports Betting
The Resolutions Committee of the California Democratic Party ...
Top Betting Sites
Top Betting Bonuses
Bet365
Bet365
Bet365 Review
4.6/5
BetMGM
BetMGM
BetMGM Review
4.6/5
FanDuel
FanDuel
FanDuel Review
4.5/5
Caesars
Caesars
Caesars Review
4.5/5
DraftKings
DraftKings
DraftKings Review
4.5/5
Bet365
Bet365 Bonus
Bet $5 & Get $150
T&Cs apply
4.6/5
Whatever the moment. It's Never Ordinary at bet365. That's why if you sign up now you will receive $150 in Bonus Bets Win or Lose when you bet $5! Minimum $10 deposit required. Minimum odds -500 of greater. Bonus Bets wager excluded from returns. New customers only. T&CS, time limits and exclusions apply. GAMBLING PROBLEM? CALL OR TEXT 1-800-GAMBLER (AZ/CO/IL/IN/KS/KY/LA/MD/NC/NJ/OH/PA/TN/VA) or 1-800-BETS OFF (IA). 21+ (18+ KY). Must be present in AZ/CO/IA/IL/IN/KS/KY/LA (select parishes)/MD/NC/NJ/OH/PA/TN/VA.
BetMGM
BetMGM Bonus
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
T&Cs apply
4.6/5
Gambling problem? Call 1-800-GAMBLER (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA) 21+ only. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). Rewards are non-withdrawable bonus bets that expire in 7 days. In partnership with Kansas Crossing Casino and Hotel. See BetMGM.com for Terms. US promotional offers not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.
FanDuel
FanDuel Bonus
Bet $5 Get $150 in Bonus Bets If Your Bet Wins!
T&Cs apply
4.5/5
Gambling Problem? Call 1-800-GAMBLER or visit RG Help . Call 1-888-789-7777 or visit Helpline and Chat - CONNECTICUT COUNCIL (CT). Hope is here. Home or call (800) 327-5050 for 24/7 support (MA). Visit Home (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ D.C.) and present in select states (for KS, in affiliation with Kansas Star Casino). First online real money wager only. $5 first deposit required. Bonus issued as nonwithdrawable bonus bets which expire 7 days after receipt. See terms at FanDuel Sportsbook
Caesars
Caesars Bonus
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost
T&Cs apply
4.5/5
21+ New users only. Must register using eligible promo code. First bet after registration must qualify. Max. Bonus Bet: $1,000. Bonus Bet expires 14 days after receipt. Void where prohibited. See Caesars.com/promos for full terms. Gambling Problem? 1-800-GAMBLER (1-800-426-2537)
DraftKings
DraftKings Bonus
New Customers: Bet $5+ and get $200 in Bonus Bets if it wins!
T&Cs apply
4.5/5
GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). Pass-thru of per wager tax may apply in IL. 1 per new customer. Must register new account to receive reward Token. Must select Token BEFORE placing min. $5 bet to receive $200 in Bonus Bets if your bet wins. Min. -500 odds req. Token and Bonus Bets are single-use and non-withdrawable. Token expires 1/11/26. Bonus Bets expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 1/4/26 at 11:59 PM ET. Sponsored by DK.
What does it take to win? Sign up now and find out!
white-paper-teaser
Winning Bettors aren’t born, they’re trained. Sign up now for our free eBook and Newsletter with the best deals on the web.

Submit your email to receive PlayersBest eBook and regular newsletters with exclusive bonus offers via email. Unsubscribe at any time.
Our Team
author2-profile
author2-profile
author2-profile
Playersbest US
What does it take to win? Sign up now and find out!
Winning Bettors aren’t born, they’re trained. Sign up now for our free eBook and Newsletter with the best deals on the web.

Submit your email to receive PlayersBest eBook and regular newsletters with exclusive bonus offers via email. Unsubscribe at any time.

21+ and present in VA. Gambling Problem? Call 1-800-GAMBLER.

This site is using Cloudflare and adheres to the Google Safe Browsing Program. We adapted Google's Privacy Guidelines to keep your data safe at all times.
Virginia Town HallCloudflareSSLcoΒ² neutral
×
Your Promo Code:
The bonus offer of was already opened in an additional window. If not, you can open it also by clicking the following link:
Play now