Brewers vs. Cardinals Prediction, Odds, and Props: Milwaukee Takes Opener

Brewers vs. Cardinals Prediction, Odds, and Props: Milwaukee Takes Opener

The St. Louis Cardinals host the Milwaukee Brewers in the opener of an NL Central series on Thursday night. Our Brewers vs. Cardinals prediction, odds analysis, and player prop picks will give you all of the information you need to join the action.

bet365 Sportsbook has the visiting Brewers as the slight moneyline favorites at -120 with a total of 7.5 runs. 

Brewers vs. Cardinals odds 

Moneyline Total (Over/Under) Run Line
Brewers (-120)Over 8 runs (-125) Brewers -1.5 runs (+120)
Cardinals (+100)Under 8 runs (-130)Cardinals +1.5 runs (-200)

Milwaukee has covered the run line in three of five games facing St. Louis this season.

How we got here 

The Brewers (55-33) took two of three games from the Arizona Diamondbacks in their last series. They are 6-4 in their last 10 games, have the second-most wins in the National League, and are atop the NL Central, six games up on the second-place Chicago Cubs. 

The Cardinals (47-40) had their three-game win streak snapped in their last game, and they are 6-2 in their last eight games. They are in third place in the NL Central, 7.5 games behind the Brew Crew. 

On the season, the Cardinals are 23-21 at home, and the Brewers are 26-15 on the road. 

Brewers vs. Cardinals betting analysis   

By the numbers 

Brewers

  • Runs – 5th
  • Team ERA – 1st

Cardinals

  • Runs – 16th
  • Team ERA – 14th

Pitching Matchup 

Shane Drohan (3-2, 3.12 ERA, 1.23 WHIP) takes the hill for the Brewers and, in his last start, gave up two runs on 6 hits in 5 2/3 innings in a 4-2 win over the Cincinnati Reds. Milwaukee has won his last two starts, and in his last three, he has allowed only three runs in 15 innings. He began the season in the bullpen and, in two relief appearances facing the Cardinals, gave up one run in 3 1/3 innings. 

Dustin May (5-6, 4.80 ERA, 1.27 WHIP) gets the nod for the Cardinals, and he was roughed up in his last start, giving up five runs in only 2/3 of an inning, but the lineup bailed him out in an 11-5 win over the Atlanta Braves. The Cardinals have won his last four starts despite giving up 11 runs in his last two, while in the two starts before that, they did not allow any runs. 

In May’s lone start against the Brewers, he gave up two runs in seven innings in a 2-1 St. Louis loss. 

Leader’s shot key in win 

In the Brewers' last game, they beat the Arizona Diamondbacks 3-2, where Jake Bauers (.266, 16 home runs, 54 RBIs), who leads the club in home runs and RBIs, hit a two-run home run. He has two home runs and five RBIs over the last six games. 

Top of the lineup getting it done 

The three players for the Brewers with the most at-bats all have over 50 RBIs: Brice Turang (.269, 12 home runs, 51 RBIs), William Contreras (.295, 9 home runs, 51 RBIs), and Jake Bauers.

Brewers have the Cardinals' number

In five games this season between these division rivals, the Brewers have won four times, including sweeping them in the last series they met. 

Walker swinging a hot bat 

Cardinals’ Jordan Walker (.292, 20 home runs, 67 RBIs) is tied for the lead in the Majors in RBIs, and in the last five games, he has two home runs and nine RBIs. 

Two again for Burleson 

St. Louis’ Alec Burleson (.281, 14 home runs, 63 RBIs) ranks tied for fourth in the bigs in RBIs, has two hits in each of the last three games, and has six RBIs in the last five games. 

Brewers vs. Cardinals prediction: Brewers moneyline (-120) 

May has been rocked, giving up a total of 11 runs in his last two starts. The St. Louis lineup bailed him out, but they will not get much in this game facing Drohan, who has only given up a total of three runs in his last three starts. 

The Brew Crew will get it done at the dish, and Drohan will have a good outing, and add those things up, and you get a Milwaukee win. 

Brewers vs. Cardinals player prop picks 

Here are some player prop bets we like at DraftKings Sportsbook:

  • Shane Drohan over 4.5 strikeouts (+115) – Drohan has 12 Ks in his last two starts, and St. Louis ranks fourth in the Majors in strikeouts per game.
  • Jake Bauers (+472) and Jordan Walker (+411) to hit a home run – Pretty solid odds for two players who lead their team in home runs and went yard in the last game.