Guardians vs. Twins Prediction, Odds and Props: Minnesota Extends Win Streak

Guardians vs. Twins Prediction, Odds and Props: Minnesota Extends Win Streak

In an AL Central series opener in the Land of 10,000 Lakes, the Minnesota Twins host the Cleveland Guardians. 

You have come to the right place for all the info on this game, including odds, player props, and pitching matchups, in this comprehensive Guardians vs. Twins prediction preview. 

At Caesars Sportsbook, the hometown Twins are the slight moneyline favorites at -120 with a total of 8.5 runs. 

Guardians vs. Twins odds 

Moneyline Total (Over/Under) Run Line
Guardians (+100)Over 8.5 runs (-110) Guardians -1.5 runs (+165)
Twins (-120)Under 8.5 runs (-103) Twins +1.5 runs (-200)

This is only the second time in the last seven games where the Twins were the moneyline favorites.

How we got here 

The Guardians (47-44) have lost two in a row after a three-game win streak and are in second place in the AL Central, only one game back of the Chicago White Sox. 

The Twins (44-47) have won two in a row and three of four games and are in third place in the division, four games out of the top spot. 

On the season, the Twins are 22-23 at home, and the Guardians are 23-22 on the road. 

Guardians vs. Twins betting analysis   

By the numbers 

Guardians

  • Runs – Tied for 26th
  • Team ERA – 9th

Twins

  • Runs – 6th
  • Team ERA – 26th

Pitching Matchup 

Joey Cantillo (7-3, 3.86 ERA, 1.36 WHIP) gets the nod for Cleveland, and in his last start, gave up two runs on only three hits in five innings in a 9-4 win over the Texas Rangers. The Guardians have won three of his last four starts, and in the three before the last one, he only gave up one run in each. 

Taj Bradley (7-3, 3.86 ERA, 1.29 WHIP) goes for the Twins and only gave up one run on four hits in five innings in his last start in an 8-3 win over the Houston Astros. Minnesota has won his last four outings, in which he gave up nine runs in 23 2/3 innings. 

Guardians shorthanded 

LF Angel Ramirez (.239, 11 home runs, 33 RBIs) and 3B Jose Martinez (.239, 10 home runs, 33 RBIs) rank first and second, respectively, in home runs and are out with injuries. 

DeLauter and Brayan Rocchio have to step up 

Chase DeLauter (.272, 8 home runs, 41 RBIs) and Brayan Rocchio (.276, 6 home runs, 37 RBIs) lead the Guardians in RBIs and have to step up with two key players out. DeLauter went yard in the last game and has four RBIs in the last five games, and Rocchio only has three RBIs in the last eight games, with them all coming in one game. 

The top online sportsbooks have the Guardians with the best odds to win the AL Central at +115, with the Twins (+650) having the third-best odds.

Minnesota lineup getting it done 

The Twins are led by their lineup, and in the three wins in their last four games, they totaled 25 runs. 

Twins may be without big bat 

AL All-Star starter Byron Buxton (.271, 25 home runs, 45 RBIs), who ranks fifth in the Majors in home runs, left the last game with an injury and is listed as day-to-day. 

Bell and Clemens are hot 

Twins’ DH Josh Bell (.247, 13 home runs, 60 RBIs) leads the club in RBIs and is swinging a hot bat with three home runs and seven RBIs over the last five games. Kody Clemens (.245, 16 home runs, 43 RBIs) has also been hot lately with three home runs and eight RBIs over the last four games. 

Minnesota leads season series so far 

In the lone series between these division rivals this season in Cleveland, the Twins won two of three games. 

Guardians vs. Twins prediction: Twins moneyline (-120) 

Going with the hotter team in this Guardians vs. Twins prediction. Both pitchers have been solid as of late and will have good outings, but the Twins have the better lineup and have been good at the dish in winning three of their last four games. 

Minnesota will take the opener and close the gap in the tight AL Central race. 

Guardians vs. Twins player prop picks 

Here are some player prop bets we like at DraftKings Sportsbook:

  • Taj Bradley 7+ strikeouts (+115) – Bradley has 18 strikeouts over his last two starts, and the Indians have averaged 12 Ks in their last three games.
  • Josh Bell 1+ RBI (+171) and Kody Clemens 1+ RBI (+175) – Great value bets here. Bell has seven RBIs over the last five games, and Clemens has eight RBIs over the last four games.