In the first game after the All-Star break for both teams, the Toronto Blue Jays play host to the Chicago White Sox on Friday night.
You can check out our White Sox vs. Blue Jays prediction to get key stats, an overview of the pitching matchup, our favorite player props, and an odds breakdown.
In the opener of this American League series, the Blue Jays are the -130 moneyline favorites north of the border at BetMGM Sportsbook, with a total of 8.5 runs.
Blue Jays vs. White Sox odds
| Moneyline | Total (Over/Under) | Run Line |
| White Sox (+110) | Over 8.5 runs (-110) | White Sox +1.5 runs (-190) |
| Blue Jays (-130) | Under 8.5 runs (-105) | Blue Jays -1.5 runs (+158) |
How we got here
Oh, what a difference a year makes. Last season, the Blue Jays (45-51) were one win away from winning the World Series, and this season, they are in the basement of the AL East.
The White Sox (50-45) had the worst record in the American League last season, but this season they're tied for first in the AL Central with the Cleveland Guardians.
White Sox vs. Blue Jays betting analysis
On the season, the Blue Jays are 24-25 at home, and the White Sox are 19-28 on the road.
By the numbers
White Sox
- Runs – 10th
- Team ERA – 11th
Blue Jays
- Runs – Tied for 26th
- Team ERA – 14th
Pitching Matchup
Anthony Kay (6-4, 4.23 ERA, 1.38 WHIP) gets the call for the Sox, and in his last start, the lefty gave up two runs in 5 1/3 innings of a 2-1 loss to the Boston Red Sox. Chicago has lost his last three starts, but he has pitched well in the last two. In his second start of the season, Kay faced Toronto, giving up two runs in a Sox win.
Blue Jays reliever Spencer Miles (4-1, 2.85 ERA, 1.10 WHIP) will be making a spot start, his third of the season out of 26 appearances. In one relief appearance against the White Sox, he tossed two scoreless innings.
Different team on the road
While the White Sox have the third most wins and the second most home wins in the AL, they are nine games under .500 on the road.
Jays are not the same lineup
Last season, the Blue Jays scored the fourth-most runs in the Majors, and this season, they rank tied for 26th.
Vladimir Guerrero Jr. (.262, 6 home runs, 41 RBIs), George Springer (.218, 9 home runs, 22 RBIs), and Addison Barger (.045, 0 home runs, 2 RBIs) — who has only played in nine games due to injury — combined for 76 home runs in 2025 and have just 16 this year.
Bo Bichette led the Jays in batting average (.311) and RBIs (94) last season and is now with the New York Mets.
Balanced offense for Sox
The White Sox have a balanced lineup. Three players have hit at least 20 home runs and four players have recorded at least 42 RBIs.
Colson Montgomery (.220, 23 home runs, 53 RBIs) leads the team in home runs, but slumped before the break with no long balls or RBIs in the last six games. Michael Vargas (.245, 21 home runs, 59 RBIs) leads the club in RBIs and went yard with four RBIs in the last four games before the break.
White Sox vs. Blue Jays prediction: Go with Under 8.5 runs (-105)
The Under presents good value in this series opener.
Chicago starter Anthony Kay has pitched well in his last two outings. Toronto starter Spencer Miles is making a spot start and will not last long before handing the ball off to a good Blue Jays’ bullpen.
Not many players will cross the plate in this one, so the Under is the pick.
Jays vs. Sox player prop picks
Here are some player prop bets we like at DraftKings Sportsbook:
- Munetaka Murakami to hit a home run (+312) – Chicago rookie Murakami has 20 home runs and was tearing it up in the first half before missing more than a month with an injury. The All-Star is due for a dinger.
- Anthony Kay to give up under 2.5 runs (-120) – Kay has not allowed more than two runs in three of his last four starts, including the last two.
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